Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 4/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL559115 | 0.89 | TACR1 (0.52) | TACR1TSHRALOX15ATMCCR5 | |
| SCHEMBL973882 | 0.88 | TACR1 (0.56) | TACR1TSHRALOX15ATMCCR5 | |
| SCHEMBL8333396 | 0.84 | TACR1 (0.54) | TACR1TSHRALOX15ATMCCR5 | |
| SCHEMBL17886657 | 0.82 | TACR1 (0.59) | TACR1TSHRALOX15ATMCCR5 | |
| SCHEMBL13594200 | 0.82 | P2RX7 (0.53) | TACR1TSHRALOX15ATMCCR5 | |
| SCHEMBL2270783 | 0.82 | TACR1 (0.61) | TACR1TSHRALOX15ATMCCR5 | |
| SCHEMBL13594170 | 0.81 | MEN1 (0.68) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4631664 | 0.81 | TACR1 (0.56) | TACR1TSHRALOX15ATMCCR5 | |
| SCHEMBL20587500 | 0.81 | TSHR (0.54) | TACR1TSHRALOX15ATMCCR5 | |
| SCHEMBL19226428 | 0.81 | TACR1 (0.60) | TACR1TSHRALOX15ATMCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |