Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594552 | 0.84 | TDP1 (0.33) | TDP1LMNAL3MBTL1 | |
| E968 SCHEMBL31738448 | 0.84 | LMNA (0.38) | TDP1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL28667172 | 0.81 | TDP1 (0.53) | TDP1 | |
| SCHEMBL7882754 | 0.78 | — | — | |
| SCHEMBL12264068 | 0.78 | — | — | |
| SCHEMBL2386043 | 0.78 | — | — | |
| SCHEMBL1988036 | 0.78 | — | — | |
| SCHEMBL13754785 | 0.78 | — | — | |
| E968 SCHEMBL29233654 | 0.77 | PDE4A (0.38) | TDP1LMNAL3MBTL1 | |
| SCHEMBL9651406 | 0.77 | TSHR (0.36) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999045947-A9 | IN VITRO FORMATION OF CONGOPHILIC MALTESE-CROSS AMYLOID PLAQUES TO IDENTIFY ANTI-PLAQUE THERAPEUTICS FOR THE TREATMENT OF ALZHEIMER'S AND PRION DISEASES | UNIV WASHINGTON (US) | 2000-03-02 | — | — | WO | claimed |