SCHEMBL8047571

SCHEMBL8047571

CC(=O)c1cc(N)ccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
KDM4E B2RXH2 6/20 0.59
TDP1 Q9NUW8 6/20 0.59
KMT2A Q03164 5/20 0.59
MAPT P10636 4/20 0.59
MEN1 O00255 4/20 0.59
THRB P10828 2/20 0.59
RECQL P46063 2/20 0.59
CYP3A4 P08684 2/20 0.59
GAA P10253 2/20 0.59
POLB P06746 2/20 0.59
ALOX15 P16050 2/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2C19 P33261 2/20 0.59
HSD17B10 Q99714 2/20 0.59
MCL1 Q07820 2/20 0.59
USP2 O75604 1/20 0.59
PKM P14618 1/20 0.59
APEX1 P27695 1/20 0.59
BLM P54132 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26054237 0.89 MAPT (0.48) ALDH1A1KDM4ETDP1KMT2AMAPT
SCHEMBL30311840 0.89 MAPT (0.48) ALDH1A1KDM4ETDP1KMT2AMAPT
SCHEMBL231377 0.87 ALDH1A1 (0.68) ALDH1A1KDM4ETDP1KMT2AMAPT
SCHEMBL29364937 0.87 ALDH1A1 (0.68) ALDH1A1KDM4ETDP1KMT2AMAPT
Piperidine SCHEMBL11200467 0.85 KDM4E (0.45) ALDH1A1KDM4ETDP1KMT2AMAPT
SCHEMBL28520448 0.85 ALDH1A1 (0.65) ALDH1A1KDM4ETDP1KMT2AMAPT
SCHEMBL2809853 0.85 ALDH1A1 (0.65) ALDH1A1KDM4ETDP1KMT2AMAPT
SCHEMBL2810654 0.85 ALDH1A1 (0.65) ALDH1A1KDM4ETDP1KMT2AMAPT
Nitrogen SCHEMBL28683357 0.83 ALDH1A1 (0.63) ALDH1A1KDM4ETDP1KMT2AMAPT
SCHEMBL33352 0.81 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114014768-B Tranexamic acid without barium salt impurity, preparation method and preparation composition thereof 南京科瑞健医药科技有限公司 2024-07-26 CN disclosed
EP-0794959-B1 AMINO ACIDS FOR MAKING BETIDES AND METHODS OF SCREENING AND MAKING BETIDE LIBRARIES SALK INST FOR BIOLOGICAL STUDI (US) 2000-04-05 EP disclosed
US-5807983-A HUMAN GONADOTROPIN RELEASING HORMONE THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1998-09-15 US disclosed
US-5807986-A GENETIC ENGINEERING THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1998-09-15 US disclosed
US-5681928-A ACYLATION, ALKYLATION OF AN AMINOGLYCINE; INSERTION INTO PEPTIDE THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1997-10-28 US disclosed
EP-0794959-A1 AMINO ACIDS FOR MAKING BETIDES AND METHODS OF SCREENING AND MAKING BETIDE LIBRARIES THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1997-09-17 EP disclosed
WO-1997022622-A1 BETIDE-SUBSTITUTED GNRH ANTAGONISTS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1997-06-26 WO disclosed
WO-1996018642-A1 AMINO ACIDS FOR MAKING BETIDES AND METHODS OF SCREENING AND MAKING BETIDE LIBRARIES THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1996-06-20 WO disclosed