Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035251 | 0.92 | MEN1 (0.50) | TDP1SMN1; SMN2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL4716443 | 0.86 | MEN1 (0.52) | TSHRTDP1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8045002 | 0.82 | ALDH1A1 (0.48) | TDP1L3MBTL1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11435584 | 0.82 | ALDH1A1 (0.49) | TSHRTDP1L3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL8047226 | 0.81 | KMT2A (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2AAGTR1 | |
| SCHEMBL1417281 | 0.81 | TDP1 (0.46) | TSHRTDP1L3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL5808786 | 0.79 | ALDH1A1 (0.50) | TSHRTDP1L3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL14577687 | 0.78 | TSHR (0.53) | TSHRL3MBTL1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL8053191 | 0.78 | SIRT2 (0.53) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL6034326 | 0.77 | MEN1 (0.52) | TSHRTDP1L3MBTL1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789020-B1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5780628-A | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0789020-A1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-13 | — | — | EP | disclosed |