Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | F3 | P13726 | 1/20 | 0.65 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.65 |
| ▸ | NAMPT | P43490 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6939501 | 0.99 | HDAC1 (0.74) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL2434821 | 0.89 | HDAC1 (0.78) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL18347845 | 0.88 | HDAC1 (0.76) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL3643968 | 0.88 | HDAC1 (0.76) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL5790114 | 0.87 | HDAC1 (0.74) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL27605535 | 0.86 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL18621504 | 0.85 | HDAC1 (0.72) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL1062974 | 0.85 | HDAC1 (0.76) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL28596954 | 0.85 | HDAC1 (0.72) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL6558145 | 0.84 | HDAC1 (0.62) | HDAC1HDAC3HDAC2HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076206-A1 | SYNTHESIS METHODS OF HISTONE DEACETYLASE INHIBITORS (HDACIS) | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2009-06-18 | — | — | WO | disclosed |