Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.49 |
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5444853 | 0.84 | PPARD (0.54) | PPARDPPARARXRARXRBRXRG | |
| SCHEMBL1592608 | 0.83 | PSEN1 (0.59) | PPARDPPARARXRARXRBRXRG | |
| SCHEMBL12724670 | 0.81 | CNR1 (0.47) | PPARDPPARAPPARGLMNAFAAH | |
| SCHEMBL478056 | 0.81 | RXRA (0.48) | PPARDPPARARXRARXRBRXRG | |
| SCHEMBL5123958 | 0.80 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL12703212 | 0.79 | PPARD (0.47) | PPARDPPARARXRARXRBRXRG | |
| SCHEMBL491285 | 0.78 | PPARD (0.49) | PPARDPPARARXRARXRBRXRG | |
| SCHEMBL5050131 | 0.78 | RXRA (0.49) | PPARDRXRARXRBRXRGPSEN1 | |
| SCHEMBL14477117 | 0.77 | CYP4F2 (0.53) | RXRARXRBRXRGPSEN1PSEN2 | |
| SCHEMBL6270689 | 0.75 | AGXT (0.56) | RXRAPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067493-A2 | 1,3,5 TRI-SUBTITUTED BENZENES FOR TREATMENT OF ALZHEIMER'S DISEASE AND OTHER DISORDERS | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | WO | disclosed |