Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL27604696 | 0.90 | ALDH1A1 (0.78) | ALDH1A1TDP1L3MBTL1SRD5A2ATM | |
| Benzophenone SCHEMBL30533417 | 0.90 | ALDH1A1 (0.78) | ALDH1A1TDP1L3MBTL1SRD5A2ATM | |
| Benzophenone SCHEMBL10558283 | 0.87 | ALDH1A1 (0.93) | ALDH1A1TDP1L3MBTL1SRD5A2ATM | |
| Benzophenone SCHEMBL27436227 | 0.84 | ALDH1A1 (0.88) | ALDH1A1TDP1L3MBTL1SRD5A2ATM | |
| Benzophenone SCHEMBL1695422 | 0.84 | ALDH1A1 (0.88) | ALDH1A1TDP1L3MBTL1SRD5A2ATM | |
| Benzophenone SCHEMBL30537001 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1SRD5A2ATM | |
| Benzophenone SCHEMBL6061130 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1SRD5A2ATM | |
| Benzophenone SCHEMBL28491203 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1SRD5A2ATM | |
| Benzophenone SCHEMBL30536983 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1SRD5A2ATM | |
| Benzophenone SCHEMBL1074283 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1SRD5A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991664-A1 | NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS INTERACTING WITH GTP-BINDING PROTEINS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2000-04-12 | — | — | EP | claimed |
| WO-1999002558-A1 | NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS INTERACTING WITH GTP-BINDING PROTEINS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1999-01-21 | — | — | WO | claimed |