Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19239961 | 0.93 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17069794 | 0.93 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11919878 | 0.93 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3397778 | 0.91 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2367838 | 0.91 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27454755 | 0.88 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9179072 | 0.88 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10115291 | 0.88 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9764030 | 0.88 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25602131 | 0.88 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063887-A | 1-acyloxy-organotetrasiloxane and production method for the preparation of the same | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5856545-A | Method for preparation of organopentasiloxane | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |