Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27454755 | 1.00 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10115291 | 1.00 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9764030 | 1.00 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2368062 | 0.98 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759270 | 0.97 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12373196 | 0.97 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17069794 | 0.95 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19239961 | 0.95 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11919878 | 0.95 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2367838 | 0.94 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773289-B2 | Organofunctional siloxanes, process for preparing same and their use for the treatment of fillings and surfaces | ABCR LABORATORIOS, S.L. (ES) | 2023-10-03 | — | — | US | disclosed |
| US-11773289-B2 | Organofunctional siloxanes, process for preparing same and their use for the treatment of fillings and surfaces | ABCR LABORATORIOS, S.L. (ES) | 2023-10-03 | — | — | US | disclosed |
| US-20200332149-A1 | ORGANOFUNCTIONAL SILOXANES, PROCESS FOR PREPARING SAME AND THEIR USE FOR THE TREATMENT OF FILLINGS AND SURFACES | ABCR LABORATORIOS, S.L. (ES) | 2020-10-22 | — | — | US | disclosed |
| EP-3543304-B1 | ORGANOFUNCTIONAL SILOXANES, METHOD FOR ITS PREPARATION AND USE FOR THE TREATMENT OF FILLERS AND SURFACES | ABCR LABORATORIOS S L (ES) | 2020-08-05 | — | — | EP | disclosed |
| EP-3543304-A1 | ORGANOFUNCTIONAL SILOXANES, METHOD FOR ITS PREPARATION AND USE FOR THE TREATMENT OF FILLERS AND SURFACES | ABCR Laboratorios, S.L. (ES) | 2019-09-25 | — | — | EP | disclosed |
| EP-0250093-B1 | Polysiloxane-grafted copolymer pressure sensitive adhesive composition and sheet materials coated therewith | MINNESOTA MINING & MFG (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0210041-B1 | POLYSILOXANE-GRAFTED COPOLYMER RELEASE COATING ON SHEET MATERIALS AND ADHESIVE TAPES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4728571-A | Polysiloxane-grafted copolymer release coating sheets and adhesive tapes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0250093-A2 | Polysiloxane-grafted copolymer pressure sensitive adhesive composition and sheet materials coated therewith | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-12-23 | — | — | EP | disclosed |
| US-4693935-A | LOW INITIAL PEEL ADHESION, POSITIONABLE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0210041-A2 | Polysiloxane-grafted copolymer release coating on sheet materials and adhesive tapes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200332149-A1 | ORGANOFUNCTIONAL SILOXANES, PROCESS FOR PREPARING SAME AND THEIR USE FOR THE TREATMENT OF FILLINGS AND SURFACES | FDFT1, DBF4, IPO4 | TSHR 4675/4885THRB 4559/4885POLB 1792/4885 |
| US-11773289-B2 | Organofunctional siloxanes, process for preparing same and their use for the treatment of fillings and surfaces | FDFT1, DBF4, IPO4 | TSHR 4675/4885THRB 4559/4885POLB 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.