SCHEMBL80491

SCHEMBL80491

[O]c1cc2ccccc2c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
HSD17B10 Q99714 5/20 0.52
HIF1A Q16665 2/20 0.52
CYP1B1 Q16678 1/20 0.52
TRPM4 Q8TD43 1/20 0.52
HPRT1 P00492 3/20 0.50
TSHR P16473 2/20 0.48
CYP2A6 P11509 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PAX8 Q06710 1/20 0.46
HPGD P15428 4/20 0.43
CYP1A2 P05177 3/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
GLA P06280 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
GPR84 Q9NQS5 1/20 0.42
MAPT P10636 2/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14354344 0.83 HPRT1 (0.64) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL14354135 0.78 ALDH1A1 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL14353870 0.77 HSD17B10 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL14354119 0.77 HSD17B10 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL3165939 0.75 HPRT1 (0.67) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL60533 0.75 HPRT1 (0.67) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL7305016 0.75 CYP1A2 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL29637136 0.75 ALDH1A1 (0.60) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL7905250 0.75 ALDH1A1 (0.60) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL14354308 0.74 ALDH1A1 (0.40) ALDH1A1HSD17B10HIF1ATRPM4HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024587-A Condensed aromatic derivative containing boron and nitrogen, method for preparing same, and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2021-06-25 CN claimed
CN-107903384-B Flame retardant type Imidazole Type Latent Curing Agent and preparation method thereof 武汉理工大学 2019-07-23 CN claimed
CN-106750239-B A kind of phosphorus-nitrogen containing silicon polymer fire retardant and the preparation method and application thereof 厦门大学 2019-02-05 CN claimed
EP-3400231-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS Technion Research & Development Foundation Limited (IL) 2018-11-14 EP claimed
CN-106397984-B A kind of preparation method of modified expansible graphite/polypropylene flameretardant material 西南交通大学 2018-10-30 CN claimed
CN-108690279-A A kind of flame retardant type composite cable 安徽伙伴电气有限公司 2018-10-23 CN claimed
EP-3344641-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS Eloxx Pharmaceuticals Ltd. (IL) 2018-07-11 EP claimed
CN-107903384-A Flame retardant type Imidazole Type Latent Curing Agent and preparation method thereof 武汉理工大学 2018-04-13 CN claimed
CN-107266849-A A kind of low temperature resistant plating PC/ABS alloy materials drawn cruelly and preparation method 上海跃贝塑化科技有限公司 2017-10-20 CN claimed
WO-2017118967-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2017-07-13 WO claimed
CN-105238418-B Aqueous halogen-free fire retardant, and preparation method and application thereof 四川大学 2017-04-26 CN claimed
WO-2017037719-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS ELOXX PHARMACEUTICALS LTD. (IL) 2017-03-09 WO claimed
CN-106432718-A Preparation method of polyamide 56 having flame retardant property and polyamide 56 fiber 辽宁银珠化纺集团有限公司 2017-02-22 CN claimed
CN-106397984-A Method for preparing modified expandable graphite/polypropylene flame-retardant material 西南交通大学 2017-02-15 CN claimed
CN-103881134-B DOPO (9,10-dihydID-9-oxa-10-phosphaphenanthrene-10-oxide)-derived phosphorus-nitrogen flame retardant as well as preparation method and application thereof 湖北大学 2017-02-15 CN claimed
CN-104341598-B A kind of MDT type activity halogen-free flame retardants and preparation method thereof 东华大学 2016-09-07 CN claimed
CN-105885754-A Low-temperature type flame retardant epoxy resin adhesive and preparation method thereof 上海大学 2016-08-24 CN claimed
US-20020034657-A1 Organic electroluminescence device NEC CORPORATION. 2002-03-21 US claimed
EP-0658818-A1 Toner compositions with compatibilizer XEROX CORPORATION (US) 1995-06-21 EP claimed
US-5368970-A Toner compositions with compatibilizer XEROX CORPORATION (US) 1994-11-29 US claimed