Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.34 |
| ▸ | THRA | P10827 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.32 |
| ▸ | TNNC1 | P63316 | 3/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047757 | 0.92 | MAOA (0.38) | THRB | |
| SCHEMBL8037737 | 0.89 | CYP3A4 (0.30) | S1PR3 | |
| SCHEMBL8049190 | 0.88 | SPHK1 (0.32) | THRBTHRASPHK1SPHK2TNNC1 | |
| SCHEMBL8049193 | 0.88 | SPHK1 (0.32) | THRBTHRASPHK1SPHK2TNNC1 | |
| SCHEMBL8055283 | 0.88 | MAOA (0.36) | — | |
| SCHEMBL8049854 | 0.85 | MAOB (0.38) | — | |
| SCHEMBL8037716 | 0.85 | TLR4 (0.36) | — | |
| SCHEMBL8047566 | 0.84 | SPHK1 (0.46) | SPHK1SPHK2 | |
| SCHEMBL8037685 | 0.84 | TSHR (0.35) | — | |
| SCHEMBL9355184 | 0.84 | SPHK1 (0.36) | SPHK1TNNC1SGPL1S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728829-B1 | Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5698136-A | LOW TEMPERATURE COMPATIBILITY, CHEMICAL STABILITY | CHISSO CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0728829-A2 | Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1996-08-28 | — | — | EP | disclosed |