Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 4/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134968 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL9135196 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL2325056 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL2319510 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL1143640 | 0.86 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL12082412 | 0.86 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL3655886 | 0.86 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL15492571 | 0.86 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL1143015 | 0.86 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL1143555 | 0.86 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008590-A1 | Process for preparing optically active oxazolidinone derivative | Takasago International Corporation (JP) | 2000-06-14 | — | — | EP | disclosed |