Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 16/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049904 | 1.00 | ESR1 (0.46) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL8044200 | 0.91 | CYP17A1 (0.40) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL8047666 | 0.91 | CYP17A1 (0.40) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL8044198 | 0.91 | CYP17A1 (0.40) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL8047663 | 0.91 | CYP17A1 (0.40) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL8052700 | 0.87 | NPC1 (0.34) | ESR1ESR2HDAC1HDAC8 | |
| SCHEMBL8052697 | 0.87 | NPC1 (0.34) | ESR1ESR2HDAC1HDAC8 | |
| SCHEMBL8047048 | 0.86 | ESR1 (0.41) | ESR1ESR2HSD17B1HSD17B2HDAC1 | |
| SCHEMBL8047051 | 0.86 | ESR1 (0.41) | ESR1ESR2HSD17B1HSD17B2HDAC1 | |
| SCHEMBL8052738 | 0.86 | ESR1 (0.34) | ESR1ESR2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643119-B1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-6030546-A | FERROELECTRIC PHASE; LOW VISCOSITY;, THERMOSENSITIVITY OVER A BROAD AND EXHIBITS A LARGE TILT ANGLE AND A HIGH-SPEED RESPONSE PROPERTY;CHEMICAL INTERMEDIATES FOR PESTICIDES, DRUGS AND LIQUID CRYSTALS; BORIDING AND HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5707547-A | CONTAINING FLUORINATED BENZENE OR NAPHTHALENE RINGS AND/OR NITROGEN CONTAINING HETEROCYCLES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0643119-A1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |