Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 9/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052700 | 1.00 | NPC1 (0.34) | NPC1RAB9ACASP3SENP7ESR1 | |
| SCHEMBL8046110 | 0.89 | CYP11B1 (0.40) | NPC1RAB9AESR1ESR2CYP11B1 | |
| SCHEMBL8046104 | 0.89 | CYP11B1 (0.40) | NPC1RAB9AESR1ESR2CYP11B1 | |
| SCHEMBL8045851 | 0.88 | NPC1 (0.40) | NPC1RAB9ACASP3SENP7HDAC1 | |
| SCHEMBL8045855 | 0.88 | NPC1 (0.40) | NPC1RAB9ACASP3SENP7HDAC1 | |
| SCHEMBL8049904 | 0.87 | ESR1 (0.46) | ESR1ESR2HDAC1HDAC8 | |
| SCHEMBL8049898 | 0.87 | ESR1 (0.46) | ESR1ESR2HDAC1HDAC8 | |
| SCHEMBL8048180 | 0.87 | NPC1 (0.31) | NPC1RAB9ACASP3SENP7ESR1 | |
| SCHEMBL8048182 | 0.87 | NPC1 (0.31) | NPC1RAB9ACASP3SENP7ESR1 | |
| SCHEMBL8045477 | 0.86 | CYP11B1 (0.39) | NPC1RAB9ACASP3SENP7ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643119-B1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-6030546-A | FERROELECTRIC PHASE; LOW VISCOSITY;, THERMOSENSITIVITY OVER A BROAD AND EXHIBITS A LARGE TILT ANGLE AND A HIGH-SPEED RESPONSE PROPERTY;CHEMICAL INTERMEDIATES FOR PESTICIDES, DRUGS AND LIQUID CRYSTALS; BORIDING AND HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5707547-A | CONTAINING FLUORINATED BENZENE OR NAPHTHALENE RINGS AND/OR NITROGEN CONTAINING HETEROCYCLES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0643119-A1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |