Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046927 | 0.88 | PTGS2 (0.43) | PTGS2STAT3MAPTTTRBACE1 | |
| SCHEMBL8046803 | 0.83 | PPARG (0.40) | PTGS2STAT3MAPTBACE1ABCG2 | |
| SCHEMBL8048204 | 0.82 | NPSR1 (0.41) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL8045679 | 0.81 | POLB (0.37) | PTGS2STAT3MAPTTTRBACE1 | |
| SCHEMBL8053110 | 0.80 | ABCG2 (0.44) | MAPTBACE1MAOBMEN1NR1I2 | |
| SCHEMBL8035838 | 0.79 | MAOB (0.40) | PTGS2MAPTTTRMAOBMEN1 | |
| SCHEMBL8053320 | 0.78 | GAA (0.44) | PTGS2MAPTTTRMEN1NR1I2 | |
| Acrylic Acid Methyl Ester SCHEMBL8046469 | 0.77 | MAOB (0.37) | MAPTTTRBACE1MAOBMEN1 | |
| SCHEMBL8045370 | 0.76 | GAA (0.49) | PTGS2MAPTMEN1NR1I2LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL2707868 | 0.73 | CA12 (0.57) | CA12CA1CA2TYRCA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6010826-A | Resist composition | NIPPON ZEON CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0786701-A1 | RESIST COMPOSITION | NIPPON ZEON CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |