Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468807 | 0.79 | MAPT (0.39) | TDP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL543282 | 0.79 | APOBEC3G (0.32) | KDM4EMAPTALDH1A1 | |
| SCHEMBL8049471 | 0.75 | MAPT (0.33) | TDP1MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8051660 | 0.75 | CYP1A2 (0.43) | TDP1KDM4ECYP1A2MAPTMEN1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.74 | ALDH1A1 (0.44) | TDP1KDM4ECYP1A2MAPTMEN1 | |
| SCHEMBL3714628 | 0.73 | MAPK9 (0.47) | AKR1B1TDP1KDM4ECYP1A2MAPT | |
| SCHEMBL8049797 | 0.71 | HTT (0.35) | KDM4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL27848468 | 0.71 | TDP1 (0.44) | AKR1B1TDP1KDM4ECYP1A2MAPT | |
| SCHEMBL3752215 | 0.70 | MAPT (0.33) | KDM4ECYP1A2MAPTMEN1ALDH1A1 | |
| SCHEMBL9368369 | 0.70 | MAPT (0.35) | KDM4EMAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502473-B1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | NOVARTIS AG (CH) | 2000-04-26 | — | — | EP | disclosed |
| US-5384321-A | Benzothiadiazole compounds | CIBA-GEIGY CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |
| US-5260423-A | Fungicide, viricide or bactericide | CIBA-GEIGY CORPORATION (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0502473-A1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | CIBA-GEIGY AG (CH) | 1992-09-09 | — | — | EP | disclosed |