⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79834 | 0.74 | — | — | |
| SCHEMBL5397886 | 0.70 | — | — | |
| SCHEMBL11471476 | 0.67 | — | — | |
| SCHEMBL9998761 | 0.67 | — | — | |
| SCHEMBL7191764 | 0.67 | — | — | |
| Trichloroethane SCHEMBL16434 | 0.65 | — | — | |
| SCHEMBL10649555 | 0.65 | — | — | |
| SCHEMBL7490 | 0.65 | — | — | |
| Trichloroethane SCHEMBL64609 | 0.65 | — | — | |
| Trichloroethane SCHEMBL3833855 | 0.65 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133467-A | ANTIATHEROSCLEROTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0996623-A1 | 2,6-DI-t-BUTYL-4- (DIMETHYL-4-METHOXYPHENYLSILYL) -METHYLOXY]PHENOL AND 2,6-DI-t-BUTYL-4- (DIMETHYL-2-METHOXY-PHENYLSILYL) -METHYLOXY]PHENOL | HOECHST MARION ROUSSEL, INC. (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0910384-A1 | METHOD OF INHIBITING VASCULAR CELL ADHESION MOLECULE-1 AND TREATING CHRONIC INFLAMMATORY DISEASES WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS | HOECHST MARION ROUSSEL, INC. (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998058937-A1 | 2,6-DI-t-BUTYL-4-[ (DIMETHYL-4-METHOXYPHENYLSILYL) -METHYLOXY]PHENOL AND 2,6-DI-t-BUTYL-4-[ (DIMETHYL-2-METHOXY-PHENYLSILYL) -METHYLOXY]PHENOL | HOECHST MARION ROUSSEL, INC. (US) | 1998-12-30 | — | — | WO | disclosed |
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |
| WO-1997040837-A1 | METHOD OF INHIBITING VASCULAR CELL ADHESION MOLECULE-1 AND TREATING CHRONIC INFLAMMATORY DISEASES WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-06 | — | — | WO | disclosed |
| EP-0583322-A1 | ANTISEROTONINES, PREPARTION THEREOF AND MEDICAMENTS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1994-02-23 | — | — | EP | disclosed |
| WO-1992019624-A1 | ANTISEROTONINES, PREPARTION THEREOF AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1992-11-12 | — | — | WO | disclosed |
| EP-0511073-A1 | Antiserotonines, their preparation and medicaments containing them | Aventis Pharma S.A. (FR) | 1992-10-28 | — | — | EP | disclosed |
| EP-0258600-B1 | PROCESS FOR PREPARING HIGHLY ELASTIC, COLD CURING POLYURETHANE FOAMS | Th. Goldschmidt AG (DE) | 1992-01-22 | — | — | EP | disclosed |
| EP-0348705-A2 | Organophilic double-ring silicilic-acid derivatives with cage structures, process for their preparation and their use | Akademie der Wissenschaften der DDR (DE) | 1990-01-03 | — | — | EP | disclosed |
| US-4751170-A | Silylation method onto surface of polymer membrane and pattern formation process by the utilization of silylation method | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0258600-A2 | Process for preparing highly elastic, cold curing polyurethane foams | Th. Goldschmidt AG (DE) | 1988-03-09 | — | — | EP | disclosed |
| US-RE31406-E | POLYSILOXANYLALKYL ACRYLATE AND ALKYL ACRYLATE COPOLYMER | SYNTEX (U.S.A.) INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4189429-A | ANTHRAQUINONE, NAPHTHAQUINONE, MONOAZO AND STYRYL DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4120570-A | POLYSILOXANYLALKYL ACRYLATE OR METHACRYLATE AND AN ALKYL ACRYLATE OR METHACRYLATE | SYNTEX (U.S.A.) INC. (US) | 1978-10-17 | — | — | US | disclosed |