Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032705 | 0.92 | MAPT (0.31) | ALDH1A1NPSR1 | |
| SCHEMBL8042037 | 0.86 | MEN1 (0.31) | — | |
| SCHEMBL8043585 | 0.83 | — | — | |
| SCHEMBL8042604 | 0.83 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL8032619 | 0.79 | POLB (0.41) | ALDH1A1 | |
| SCHEMBL8046634 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRNPSR1 | |
| SCHEMBL8042760 | 0.77 | ATM (0.47) | ALDH1A1 | |
| SCHEMBL8032336 | 0.75 | PTGS1 (0.32) | — | |
| SCHEMBL8047168 | 0.75 | APEX1 (0.33) | — | |
| SCHEMBL8037024 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |