Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25497550 | 0.84 | ACE2 (0.47) | POLBNPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL3805383 | 0.84 | RARB (0.51) | POLBNPC1RAB9ACYP2C9MYC | |
| SCHEMBL25497533 | 0.84 | POLB (0.44) | POLBNPC1RAB9ACYP2C9TDP1 | |
| SCHEMBL8778664 | 0.83 | TDP1 (0.43) | POLBTDP1MYCKDM4EACE2 | |
| SCHEMBL13926357 | 0.83 | CDC25B (0.49) | POLBNPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL28779825 | 0.82 | PTPN11 (0.46) | POLBKMT2AMEN1APEX1CTDSP1 | |
| SCHEMBL3897415 | 0.82 | MEN1 (0.44) | POLBNPC1RAB9ATDP1MYC | |
| SCHEMBL28779811 | 0.81 | PTPN11 (0.48) | TSHRRARB | |
| SCHEMBL6309093 | 0.81 | TDP1 (0.50) | POLBTDP1MYCKDM4EACE2 | |
| SCHEMBL1355541 | 0.81 | TDP1 (0.54) | POLBTDP1MYCKDM4EACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991699-A1 | TWO-STAGE SOLUTION POLYMERIZATION OF HIGH MOLECULAR WEIGHT POLY(PHOSPHOESTERS) | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998058012-A1 | TWO-STAGE SOLUTION POLYMERIZATION OF HIGH MOLECULAR WEIGHT POLY(PHOSPHOESTERS) | GUILFORD PHARMACEUTICALS INC. (US) | 1998-12-23 | — | — | WO | disclosed |