Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618045 | 0.84 | TDP1 (0.46) | TDP1ACE2MYCKDM4EPOLB | |
| SCHEMBL8050752 | 0.83 | POLB (0.46) | TDP1ACE2MYCKDM4EPOLB | |
| Ethylene SCHEMBL9718947 | 0.81 | TDP1 (0.44) | TDP1ACE2MYCKDM4EPOLB | |
| SCHEMBL10566065 | 0.78 | ESR1 (0.46) | TDP1MYCPOLBTSHREPHX2 | |
| SCHEMBL6309093 | 0.78 | TDP1 (0.50) | TDP1ACE2MYCKDM4EPOLB | |
| SCHEMBL1355541 | 0.78 | TDP1 (0.54) | TDP1ACE2MYCKDM4EPOLB | |
| SCHEMBL23519696 | 0.78 | TDP1 (0.41) | TDP1ACE2MYCKDM4EPOLB | |
| SCHEMBL4543961 | 0.77 | KDM4E (0.44) | TDP1ACE2MYCKDM4EPOLB | |
| SCHEMBL125461 | 0.77 | TDP1 (0.49) | TDP1ACE2MYCKDM4EPOLB | |
| SCHEMBL8459721 | 0.77 | ACE2 (0.51) | TDP1ACE2MYCKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583743-B1 | Process for the production of monomeric terephthalic acid diesters and diols from polyesters | HOECHST AG (DE) | 1997-01-15 | — | — | EP | disclosed |
| EP-0583743-A2 | Process for the production of monomeric terephthalic acid diesters and diols from polyesters | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-23 | — | — | EP | disclosed |