Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 12/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
| ▸ | TTPA | P49638 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285802 | 0.87 | PSEN1 (0.42) | PSEN1MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL13108840 | 0.82 | PSEN1 (0.60) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL21344344 | 0.80 | PTGS1 (0.38) | PSEN1MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL19910935 | 0.78 | PTGS1 (0.43) | PSEN1MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL2143228 | 0.77 | PSEN1 (0.43) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL2141185 | 0.77 | PSEN1 (0.43) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL19899579 | 0.76 | MEN1 (0.42) | PSEN1MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL11358821 | 0.75 | MEN1 (0.52) | PSEN1MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL19899581 | 0.75 | PTGS1 (0.44) | PSEN1MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL11358826 | 0.75 | MEN1 (0.52) | PSEN1MEN1KMT2APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763527-B1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-04-26 | — | — | EP | disclosed |
| US-5734077-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, TREATMENT OF DIABETES AND ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 1998-03-31 | — | — | US | disclosed |
| US-5627205-A | ANTILIPEMIC AGENTS AND ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 1997-05-06 | — | — | US | disclosed |
| EP-0763527-A1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-03-19 | — | — | EP | disclosed |
| US-5512595-A | FOR SUPPRESSION OF MEMBRANE LIPID PEROXIDATION, ANTILIPEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |