SCHEMBL8052006

SCHEMBL8052006

CCCCCCCCN(Cc1nc2c(F)c(F)cc(F)c2s1)C(=O)CCC(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8055766 1.00 AKR1B1 (0.36) AKR1B1
SCHEMBL8055727 1.00 AKR1B1 (0.36) AKR1B1
SCHEMBL8052036 1.00 AKR1B1 (0.36) AKR1B1
SCHEMBL8052052 1.00 AKR1B1 (0.36) AKR1B1
SCHEMBL8053647 0.99 AKR1B1 (0.37) AKR1B1
SCHEMBL8055749 0.96 AKR1B1 (0.37) AKR1B1
SCHEMBL8053609 0.92 AKR1B1 (0.38) AKR1B1
SCHEMBL8052039 0.89 AKR1A1 (0.42) AKR1B1
SCHEMBL8055773 0.89 AKR1A1 (0.42) AKR1B1
SCHEMBL8040877 0.89 AKR1A1 (0.42) AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719767-B1 SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF SENJU PHARMA CO (JP) 2000-05-03 EP claimed
US-5688818-A ENZYME INHIBITORS SENJU PHARMACEUTICAL CO., LTD. (JP) 1997-11-18 US claimed
EP-0719767-A1 SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Senju Pharmaceutical Co., Ltd. (JP) 1996-07-03 EP claimed
EP-0719767-B1 SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF SENJU PHARMA CO (JP) 2000-05-03 EP disclosed
US-5688818-A ENZYME INHIBITORS SENJU PHARMACEUTICAL CO., LTD. (JP) 1997-11-18 US disclosed
EP-0719767-A1 SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Senju Pharmaceutical Co., Ltd. (JP) 1996-07-03 EP disclosed