Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 10/20 | 0.48 |
| ▸ | EPHB3 | P54753 | 3/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234709 | 0.93 | FGFR4 (0.46) | FGFR4EPHB3IRAK4ROCK1 | |
| SCHEMBL13099744 | 0.89 | FGFR4 (0.43) | FGFR4EPHB3IRAK4ROCK1 | |
| SCHEMBL8042726 | 0.89 | EPHB3 (0.46) | FGFR4EPHB3IRAK4ROCK1 | |
| SCHEMBL3242268 | 0.88 | FGFR4 (0.42) | FGFR4EPHB3IRAK4ROCK1 | |
| SCHEMBL8042722 | 0.86 | FGFR1 (0.43) | FGFR4EPHB3 | |
| SCHEMBL8031078 | 0.86 | FGFR4 (0.41) | FGFR4EPHB3IRAK4ROCK1 | |
| SCHEMBL3227639 | 0.85 | FGFR1 (0.41) | FGFR4EPHB3 | |
| SCHEMBL29923111 | 0.85 | FGFR1 (0.41) | FGFR4EPHB3 | |
| SCHEMBL7954698 | 0.85 | FGFR1 (0.41) | FGFR4EPHB3 | |
| SCHEMBL13099745 | 0.85 | POLB (0.42) | FGFR4EPHB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038385-A2 | NOVEL COMPOUNDS HAVING INDAZOLE FRAMEWORKS, METHODS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHOONGWAE PHARMA CORPORATION (KR) | 2009-03-26 | — | — | WO | disclosed |