Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227639 | 0.95 | FGFR1 (0.41) | FGFR1KDRHDAC6EPHB3FGFR4 | |
| SCHEMBL29923111 | 0.95 | FGFR1 (0.41) | FGFR1KDRHDAC6EPHB3FGFR4 | |
| SCHEMBL3233985 | 0.90 | RAB9A (0.42) | FGFR1KDREPHB3FGFR4FGFR2 | |
| SCHEMBL3242268 | 0.89 | FGFR4 (0.42) | FGFR1KDRHDAC6EPHB3FGFR4 | |
| SCHEMBL3234709 | 0.88 | FGFR4 (0.46) | EPHB3FGFR4MAPTMEN1KMT2A | |
| SCHEMBL8031078 | 0.87 | FGFR4 (0.41) | FGFR1KDREPHB3FGFR4 | |
| SCHEMBL8052018 | 0.85 | FGFR4 (0.48) | EPHB3FGFR4 | |
| SCHEMBL3231677 | 0.85 | GSK3B (0.49) | — | |
| SCHEMBL13099744 | 0.84 | FGFR4 (0.43) | FGFR1KDREPHB3FGFR4 | |
| SCHEMBL13099651 | 0.83 | CDK1 (0.40) | EPHB3SMN1; SMN2KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027114-A1 | USE OF PYRAZOLE-PYRIDINE DERIVATIVES AND ITS SALTS FOR TREATING OR REVENTIN OSTEOPOROSIS | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-11 | — | — | WO | disclosed |