Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279513 | 1.00 | TSHR (0.49) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL10610014 | 1.00 | TSHR (0.49) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL29044528 | 1.00 | TSHR (0.49) | TSHREPHX1LMNAFAAHZDHHC20 | |
| Hydrochloric Acid SCHEMBL725775 | 0.98 | TSHR (0.47) | TSHREPHX1LMNAFAAHZDHHC20 | |
| Hydrochloric Acid SCHEMBL29131465 | 0.98 | TSHR (0.47) | TSHREPHX1LMNAFAAHZDHHC20 | |
| Iodide SCHEMBL28815267 | 0.98 | TSHR (0.47) | TSHREPHX1LMNAFAAHZDHHC20 | |
| Bromide SCHEMBL28897725 | 0.98 | TSHR (0.47) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL9274701 | 0.98 | TSHR (0.46) | TSHREPHX1LMNAFAAHZDHHC20 | |
| Carbamic Acid SCHEMBL27513553 | 0.94 | TSHR (0.44) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL331326 | 0.93 | TSHR (0.43) | TSHREPHX1LMNAFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994911-A1 | PROCESS FOR PRODUCING AN ADHERENT POLYMERIC LAYER ON POLYMERIC SUBSTRATES AND ARTICLES PRODUCED THEREBY | PPG Industries Ohio, Inc. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999000448-A1 | PROCESS FOR PRODUCING AN ADHERENT POLYMERIC LAYER ON POLYMERIC SUBSTRATES AND ARTICLES PRODUCED THEREBY | TRANSITIONS OPTICAL, INC. (US) | 1999-01-07 | — | — | WO | disclosed |
| EP-0187137-B1 | COLORED CONTACT LENSES AND METHOD FOR MAKING SAME | SCHERING CORPORATION (US) | 1990-07-11 | — | — | EP | disclosed |
| US-4668240-A | COATING POLYMER LENS WITH COLORANT, BINDER POLYMER; ISOCYANATES, EPOXIDES | SCHERING CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0187137-A2 | Colored contact lenses and method for making same | SCHERING CORPORATION (US) | 1986-07-09 | — | — | EP | disclosed |
| US-4163092-A | QUATERNIZED MONOMER, CROSS-LINKING AGENT | PLASTOMEDICAL SCIENCES, INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4060678-A | Cationic hydrogels based on hydroxyalkyl acrylates and methacrylates | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4058491-A | Cationic hydrogels based on heterocyclic N-vinyl monomers | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-11-15 | — | — | US | disclosed |