Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29131465 | 1.00 | TSHR (0.47) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL29044528 | 0.98 | TSHR (0.49) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL10610014 | 0.98 | TSHR (0.49) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL8052192 | 0.98 | TSHR (0.49) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL9279513 | 0.98 | TSHR (0.49) | TSHREPHX1LMNAFAAHZDHHC20 | |
| Bromide SCHEMBL28897725 | 0.97 | TSHR (0.47) | TSHREPHX1LMNAFAAHZDHHC20 | |
| Iodide SCHEMBL28815267 | 0.97 | TSHR (0.47) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL9274701 | 0.97 | TSHR (0.46) | TSHREPHX1LMNAFAAHZDHHC20 | |
| Carbamic Acid SCHEMBL27513553 | 0.93 | TSHR (0.44) | TSHREPHX1LMNAFAAHZDHHC20 | |
| SCHEMBL331326 | 0.92 | TSHR (0.43) | TSHREPHX1LMNAFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3639066-B1 | CELL GROWTH INHIBITING COPOLYMER FOR USE IN OPHTHALMIC IMPLANTS | SHIUEY YICHIEH (US) | 2025-10-29 | — | — | EP | claimed |
| US-11185609-B2 | Cell growth inhibiting copolymer for use in ophthalmic implants | KeraMed, Inc. (US) | 2021-11-30 | — | — | US | claimed |
| EP-3639066-A1 | CELL GROWTH INHIBITING COPOLYMER FOR USE IN OPHTHALMIC IMPLANTS | Shiuey, Yichieh (US) | 2020-04-22 | — | — | EP | claimed |
| WO-2018232025-A1 | CELL GROWTH INHIBITING COPOLYMER FOR USE IN OPHTHALMIC IMPLANTS | SHIUEY YICHIEH (US) | 2018-12-20 | — | — | WO | claimed |
| US-20180361018-A1 | CELL GROWTH INHIBITING COPOLYMER FOR USE IN OPHTHALMIC IMPLANTS | SHIUEY YICHIEH (US) | 2018-12-20 | — | — | US | claimed |
| US-8889196-B2 | Dental composites comprising nanoparticles of amorphous calcium phosphate | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-11-18 | — | — | US | claimed |
| EP-2588140-A2 | DENTAL COMPOSITES COMPRISING NANOPARTICLES OF AMORPHOUS CALCIUM PHOSPHATE | University of Maryland, Baltimore (US) | 2013-05-08 | — | — | EP | claimed |
| US-20130108708-A1 | DENTAL COMPOSITES COMPRISING NANOPARTICLES OF AMORPHOUS CALCIUM PHOSPHATE | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2013-05-02 | — | — | US | claimed |
| WO-2012003290-A2 | DENTAL COMPOSITES COMPRISING NANOPARTICLES OF AMORPHOUS CALCIUM PHOSPHATE | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2012-01-05 | — | — | WO | claimed |
| EP-3639066-B1 | CELL GROWTH INHIBITING COPOLYMER FOR USE IN OPHTHALMIC IMPLANTS | SHIUEY YICHIEH (US) | 2025-10-29 | — | — | EP | disclosed |
| US-11185609-B2 | Cell growth inhibiting copolymer for use in ophthalmic implants | KeraMed, Inc. (US) | 2021-11-30 | — | — | US | disclosed |
| US-10813849-B2 | Rechargeable calcium phosphate-containing dental materials | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-10-27 | — | — | US | disclosed |
| EP-3639066-A1 | CELL GROWTH INHIBITING COPOLYMER FOR USE IN OPHTHALMIC IMPLANTS | Shiuey, Yichieh (US) | 2020-04-22 | — | — | EP | disclosed |
| US-20190290550-A1 | METFORMIN-CONTAINING DENTAL MATERIALS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2019-09-26 | — | — | US | disclosed |
| US-20140242195-A1 | AUTOMOTIVE SURFACE CONDITIONING SYSTEM | AMERICAN COVERS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| WO-2014062347-A1 | ANTIBACTERIAL MONOMERS, ANTIBACTERIAL RESINS AND DENTAL COMPOSITES COMPRISING THE ANTIBACTERIAL RESINS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-04-24 | — | — | WO | disclosed |
| WO-2013119901-A1 | NANOSTRUCTURED ANTIBACTERIAL AND REMINERALIZING DENTAL BONDING AGENTS AND DENTAL BONDING SYSTEMS | UNIVERSITY OF MARYLAND (US) | 2013-08-15 | — | — | WO | disclosed |
| EP-2588140-A2 | DENTAL COMPOSITES COMPRISING NANOPARTICLES OF AMORPHOUS CALCIUM PHOSPHATE | University of Maryland, Baltimore (US) | 2013-05-08 | — | — | EP | disclosed |
| US-20130108708-A1 | DENTAL COMPOSITES COMPRISING NANOPARTICLES OF AMORPHOUS CALCIUM PHOSPHATE | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2012003290-A2 | DENTAL COMPOSITES COMPRISING NANOPARTICLES OF AMORPHOUS CALCIUM PHOSPHATE | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2012-01-05 | — | — | WO | disclosed |