Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.62 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.57 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053866 | 0.91 | FOLH1 (0.59) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8055987 | 0.87 | FOLH1 (0.65) | FOLH1GRM3NAALAD2 | |
| SCHEMBL17509734 | 0.85 | FOLH1 (0.53) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7053863 | 0.85 | FOLH1 (0.54) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8058910 | 0.80 | FOLH1 (0.65) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7049641 | 0.80 | FOLH1 (0.51) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7049063 | 0.78 | FOLH1 (0.67) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7054614 | 0.78 | FOLH1 (0.57) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7051900 | 0.78 | FOLH1 (0.61) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8040925 | 0.77 | FOLH1 (0.76) | FOLH1GRM3NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054444-A | INHIBIT N-ACETYLATED ALPHA-LINKED ACIDIC DIPEPTIDASE (NAALADASE) ENZYME ACTIVITY | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-25 | — | — | US | claimed |