Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.76 |
| ▸ | CPA3 | P15088 | 1/20 | 0.52 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053977 | 0.92 | FOLH1 (0.73) | FOLH1CPA3GRM3NAALAD2 | |
| SCHEMBL8052865 | 0.86 | FOLH1 (1.00) | FOLH1CPA3GRM3NAALAD2 | |
| SCHEMBL12145183 | 0.81 | GRM3 (0.68) | FOLH1CPA3GRM3 | |
| SCHEMBL5053123 | 0.80 | FOLH1 (0.61) | FOLH1CPA3GRM3 | |
| SCHEMBL26619890 | 0.79 | FOLH1 (0.60) | FOLH1CPA3 | |
| SCHEMBL8056003 | 0.78 | FOLH1 (0.67) | FOLH1CPA3GRM3NAALAD2 | |
| SCHEMBL8052218 | 0.77 | FOLH1 (0.62) | FOLH1GRM3NAALAD2 | |
| SCHEMBL14720055 | 0.77 | FOLH1 (0.59) | FOLH1CPA3GRM3NAALAD2 | |
| SCHEMBL1374848 | 0.77 | FOLH1 (0.59) | FOLH1CPA3GRM3 | |
| SCHEMBL6381682 | 0.77 | FOLH1 (0.78) | FOLH1CPA3GRM3NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054444-A | INHIBIT N-ACETYLATED ALPHA-LINKED ACIDIC DIPEPTIDASE (NAALADASE) ENZYME ACTIVITY | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-25 | — | — | US | claimed |