Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.51 |
| ▸ | RELA | Q04206 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666128 | 0.81 | APP (0.68) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL8532307 | 0.81 | APP (0.67) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL9436073 | 0.81 | APP (0.63) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL12687416 | 0.78 | APP (0.63) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL2246561 | 0.78 | APP (0.63) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL7104770 | 0.76 | TP53 (0.67) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL2245276 | 0.76 | APP (0.63) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL28035197 | 0.73 | MAPT (0.59) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL18280700 | 0.73 | APP (0.70) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL28822619 | 0.73 | MAPT (0.55) | APPMMP9MMP8MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034246-A | ANTICANCER AGENT | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-03-07 | — | — | US | disclosed |