Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.67 |
| ▸ | MMP9 | P14780 | 2/20 | 0.67 |
| ▸ | MMP8 | P22894 | 2/20 | 0.67 |
| ▸ | MMP2 | P08253 | 1/20 | 0.67 |
| ▸ | MMP13 | P45452 | 1/20 | 0.67 |
| ▸ | ILK | Q13418 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.55 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666128 | 0.88 | APP (0.68) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL17086888 | 0.85 | APP (0.65) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL9436073 | 0.84 | APP (0.63) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL2246561 | 0.84 | APP (0.63) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL12687416 | 0.84 | APP (0.63) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL2245276 | 0.82 | APP (0.63) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL8536132 | 0.81 | APP (0.63) | APPILKRAB9AMEN1KMT2A | |
| SCHEMBL8052243 | 0.81 | APP (0.55) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL1992041 | 0.80 | APP (1.00) | APPMMP9MMP8MMP2MMP13 | |
| SCHEMBL4224543 | 0.80 | APP (0.86) | APPMMP9MMP8MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581245-B1 | Water-insoluble azo colouring agents | CLARIANT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5428136-A | Water-insoluble azo colorants having two azo groups and a 1,4-bis (acetoacetylamino) benzene coupling component | HOECHST AG (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0581245-A1 | Water-insoluble azo colouring agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | disclosed |