Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10065856 | 0.95 | ACE (0.56) | ACEMMEXIAPF10 | |
| SCHEMBL14269348 | 0.89 | ACE (0.54) | ACEMME | |
| SCHEMBL10131994 | 0.88 | MMP1 (0.42) | ACEMMEXIAPMMP1MMP3 | |
| SCHEMBL10331834 | 0.88 | MMP1 (0.42) | ACEMMEXIAPMMP1MMP3 | |
| SCHEMBL12253675 | 0.88 | MMP1 (0.42) | ACEMMEXIAPMMP1MMP3 | |
| SCHEMBL16838509 | 0.86 | ACE (0.43) | ACEMMEXIAPMMP1MMP3 | |
| SCHEMBL13383857 | 0.86 | F10 (0.53) | ACEF10 | |
| SCHEMBL14170124 | 0.85 | MMP1 (0.57) | ACEMMEXIAPMMP1MMP3 | |
| SCHEMBL10941726 | 0.84 | ACE (0.59) | ACEMMEXIAPMMP1MMP3 | |
| SCHEMBL12838126 | 0.84 | MMP1 (0.45) | ACEMMEXIAPMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071329-A1 | METHODS FOR IDENTIFYING COMPOUNDS OF INTEREST USING ENCODED LIBRARIES | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | US | disclosed |
| US-7989395-B2 | Methods for identifying compounds of interest using encoded libraries | GLAXOSMITHKLINE LLC (US) | 2011-08-02 | — | — | US | disclosed |
| US-7972992-B2 | Solid phase synthesis | PRAECIS PHARMACEUTICALS, INC. (US) | 2011-07-05 | — | — | US | disclosed |