Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052596 | 1.00 | SHBG (0.36) | SHBGSRD5A1KDM1AMEN1KMT2A | |
| SCHEMBL8038167 | 0.78 | SHBG (0.40) | SHBGSRD5A1KDM1A | |
| SCHEMBL8048190 | 0.78 | SHBG (0.40) | SHBGSRD5A1KDM1A | |
| SCHEMBL8048188 | 0.78 | SHBG (0.40) | SHBGSRD5A1KDM1A | |
| SCHEMBL7213772 | 0.67 | SHBG (0.44) | SHBGLMNASTS | |
| SCHEMBL26237102 | 0.66 | SRD5A1 (0.46) | SRD5A1KDM1ALMNATDP1 | |
| SCHEMBL978478 | 0.64 | SHBG (0.36) | SHBGSTS | |
| SCHEMBL7213776 | 0.63 | SHBG (0.55) | SHBGLMNASTS | |
| SCHEMBL13725675 | 0.63 | SHBG (0.70) | SHBGMEN1KMT2ALMNASTS | |
| SCHEMBL11096655 | 0.63 | SHBG (0.70) | SHBGMEN1KMT2ALMNASTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882735-B1 | 9 Alpha-hydroxy-8 alpha-estra-1,3,5(10)-trienes and a process for their preparation | JENAPHARM GMBH (DE) | 2000-04-19 | — | — | EP | disclosed |
| EP-0882735-A1 | 9 Alpha-hydroxy-8 alpha-estra-1,3,5(10)-trienes and a process for their preparation | Jenapharm GmbH & Co. KG (DE) | 1998-12-09 | — | — | EP | disclosed |