Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066940 | 0.94 | PTPN1 (0.55) | MAOBPTPN1ABCG2APPALDH1A1 | |
| SCHEMBL8069096 | 0.91 | PTPN1 (0.55) | MAOBPTPN1ABCG2TNFRSF1AAPP | |
| SCHEMBL8063139 | 0.90 | TNFRSF1A (0.53) | MAOBPTPN1ABCG2TNFRSF1AAPP | |
| SCHEMBL8052867 | 0.89 | TNFRSF1A (0.58) | PTPN1ABCG2TNFRSF1APDE4APDE4B | |
| SCHEMBL8064254 | 0.89 | TNFRSF1A (0.55) | MAOBPTPN1ABCG2TNFRSF1APDE4A | |
| SCHEMBL8064252 | 0.89 | TNFRSF1A (0.55) | MAOBPTPN1ABCG2TNFRSF1APDE4A | |
| SCHEMBL17237769 | 0.87 | MAOB (0.67) | MAOBPTPN1ABCG2TNFRSF1AAPP | |
| SCHEMBL27816898 | 0.84 | KRAS (0.67) | MAOBPTPN1ABCG2TNFRSF1ACXCL12 | |
| SCHEMBL8066764 | 0.83 | TNFRSF1A (0.54) | PTPN1ABCG2TNFRSF1AMAPTPDE4A | |
| SCHEMBL8069081 | 0.83 | TNFRSF1A (0.52) | MAOBPTPN1ABCG2TNFRSF1APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | disclosed |