Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052896 | 0.91 | MAOB (0.61) | PTPN1MAOBABCG2APPPDE4A | |
| SCHEMBL8066940 | 0.89 | PTPN1 (0.55) | PTPN1MAOBABCG2APPPDE4A | |
| SCHEMBL8063139 | 0.85 | TNFRSF1A (0.53) | PTPN1MAOBABCG2APPPDE4A | |
| SCHEMBL8052867 | 0.84 | TNFRSF1A (0.58) | PTPN1ABCG2PDE4APDE4BPDE4C | |
| SCHEMBL8064254 | 0.84 | TNFRSF1A (0.55) | PTPN1MAOBABCG2PDE4APDE4B | |
| SCHEMBL8064252 | 0.84 | TNFRSF1A (0.55) | PTPN1MAOBABCG2PDE4APDE4B | |
| SCHEMBL8066764 | 0.79 | TNFRSF1A (0.54) | PTPN1ABCG2PDE4APDE4BPDE4C | |
| SCHEMBL17237769 | 0.79 | MAOB (0.67) | PTPN1MAOBABCG2APPMEN1 | |
| SCHEMBL8069081 | 0.79 | TNFRSF1A (0.52) | PTPN1MAOBABCG2PDE4APDE4B | |
| SCHEMBL8066918 | 0.78 | TNFRSF1A (0.51) | PTPN1ABCG2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |