Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064391 | 0.97 | PTPN1 (0.56) | PTPN1TNFRSF1AMAOBMEN1POLB | |
| SCHEMBL17237769 | 0.86 | MAOB (0.67) | PTPN1TNFRSF1AMAOBMEN1KMT2A | |
| SCHEMBL8052867 | 0.85 | TNFRSF1A (0.58) | PTPN1TNFRSF1AABCG2ABCB1NPC1 | |
| SCHEMBL8064254 | 0.83 | TNFRSF1A (0.55) | PTPN1TNFRSF1AMAOBABCG2NPC1 | |
| SCHEMBL8064252 | 0.83 | TNFRSF1A (0.55) | PTPN1TNFRSF1AMAOBABCG2NPC1 | |
| SCHEMBL4883621 | 0.83 | ABCG2 (0.65) | PTPN1MAOBMEN1POLBKMT2A | |
| SCHEMBL5318918 | 0.83 | ABCG2 (0.65) | PTPN1MAOBMEN1POLBKMT2A | |
| SCHEMBL27705774 | 0.82 | MAOB (0.71) | PTPN1TNFRSF1AMAOBMEN1KMT2A | |
| SCHEMBL27705775 | 0.82 | MAOB (0.71) | PTPN1TNFRSF1AMAOBMEN1KMT2A | |
| SCHEMBL8066764 | 0.82 | TNFRSF1A (0.54) | PTPN1TNFRSF1AABCG2ABCB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |