Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052936 | 0.97 | PTPN1 (0.57) | PTPN1TNFRSF1AMAOBMEN1POLB | |
| SCHEMBL17237769 | 0.87 | MAOB (0.67) | PTPN1HDAC8TNFRSF1AMAOBMEN1 | |
| SCHEMBL8064254 | 0.87 | TNFRSF1A (0.55) | PTPN1SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL8064252 | 0.87 | TNFRSF1A (0.55) | PTPN1SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL5318918 | 0.85 | ABCG2 (0.65) | PTPN1MAOBMEN1POLBKMT2A | |
| SCHEMBL4883621 | 0.85 | ABCG2 (0.65) | PTPN1MAOBMEN1POLBKMT2A | |
| SCHEMBL8052867 | 0.84 | TNFRSF1A (0.58) | PTPN1SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL16246460 | 0.83 | TNFRSF1A (0.76) | SMPD1HDAC1HDAC8HDAC6TNFRSF1A | |
| SCHEMBL16246459 | 0.83 | TNFRSF1A (0.76) | SMPD1HDAC1HDAC8HDAC6TNFRSF1A | |
| SCHEMBL8063139 | 0.83 | TNFRSF1A (0.53) | PTPN1SMPD1HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |