Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Resorcinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | CA12 | O43570 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | CA9 | Q16790 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resorcinol SCHEMBL8053030 | 1.00 | ALDH1A1 (0.67) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL28808633 | 0.94 | ALDH1A1 (0.67) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL28077653 | 0.92 | ALDH1A1 (0.63) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL27726709 | 0.90 | ALDH1A1 (0.60) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL6002779 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL27654350 | 0.82 | ALDH1A1 (0.75) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL5404097 | 0.82 | ALDH1A1 (0.75) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL258586 | 0.82 | ALDH1A1 (0.75) | ALDH1A1CA12CA2CA9CYP3A4 | |
| Resorcinol SCHEMBL15515 | 0.82 | — | — | |
| Resorcinol SCHEMBL326229 | 0.82 | CA12 (1.00) | ALDH1A1CA12CA2CA9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075158-A | CATALYTIC REACTING A TRIARYL PHOSPHATE WITH AN ALCOHOL IN THE PRESENCE OF A BASE TO PRODUCE THE PHOSPHATE ESTER PRODUCT | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-06-13 | — | — | US | disclosed |
| EP-0775147-A1 | TRANSESTERIFICATION PROCESS | FMC Corporation (UK) Limited (GB) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005208-A1 | TRANSESTERIFICATION PROCESS | FMC CORPORATION (UK) LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |