Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26306431 | 0.96 | DNM1 (0.66) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL612928 | 0.96 | DNM1 (0.66) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL8572888 | 0.96 | DNM1 (0.55) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL11143971 | 0.95 | MEN1 (0.67) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL25285878 | 0.94 | DNM1 (0.68) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL10544914 | 0.94 | DNM1 (0.68) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL6542825 | 0.94 | DNM1 (0.68) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL25287115 | 0.94 | DNM1 (0.68) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL1839966 | 0.94 | DNM1 (0.68) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL27706358 | 0.94 | DNM1 (0.68) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758643-B1 | Process for the preparation of ortho-nitro-benzonitriles | CLARIANT GMBH (DE) | 2000-05-17 | — | — | EP | disclosed |
| US-5705674-A | Process for preparing ortho-nitrobenzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | disclosed |
| EP-0758643-A2 | Process for the preparation of ortho-nitro-benzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-19 | — | — | EP | disclosed |