Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 13/20 | 0.46 |
| ▸ | CHAT | P28329 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 13/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8053374 | 1.00 | CHAT (0.47) | CHATBCHEACHE | |
| Bromide SCHEMBL8047158 | 0.98 | CHAT (0.49) | CHATBCHEACHE | |
| Bromide SCHEMBL29216858 | 0.81 | CHAT (0.68) | CHATACHE | |
| SCHEMBL10615942 | 0.78 | KDM4A (0.57) | CHATACHE | |
| SCHEMBL10615946 | 0.78 | KDM4A (0.57) | CHATACHE | |
| Bromide SCHEMBL7919286 | 0.76 | BCHE (0.71) | BCHEACHE | |
| SCHEMBL13030887 | 0.75 | CHAT (0.59) | CHAT | |
| Bromide SCHEMBL8155184 | 0.75 | CHAT (0.60) | CHATACHE | |
| Bromide SCHEMBL8155034 | 0.75 | CHAT (0.60) | CHATACHE | |
| Bromide SCHEMBL7927418 | 0.74 | BCHE (0.76) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020436-A | GRAFT POLYMERIZATION | THE CHROMALINE CORPORATION (US) | 2000-02-01 | — | — | US | disclosed |
| US-5506089-A | CONTAINING HETEROCYCLIC QUATERNARY PENDANT GROUP | THE CHROMALINE CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |