Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | RHOA | P61586 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22461737 | 0.92 | HTT (0.67) | HPGDHTTL3MBTL1RHOAALDH1A1 | |
| SCHEMBL10720750 | 0.91 | RECQL (0.68) | HPGDHTTL3MBTL1RECQLCA12 | |
| SCHEMBL22688332 | 0.86 | RECQL (0.62) | HPGDHTTRECQLCA12CA1 | |
| SCHEMBL12965 | 0.86 | HPGD (0.67) | HPGDHTTL3MBTL1RHOAALDH1A1 | |
| SCHEMBL10329768 | 0.85 | HTT (0.65) | HPGDHTTL3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL472231 | 0.85 | RECQL (0.60) | HPGDHTTL3MBTL1RECQLCA12 | |
| SCHEMBL12156603 | 0.85 | RECQL (0.60) | HPGDHTTRECQLCA12CA1 | |
| SCHEMBL18166095 | 0.84 | RECQL (0.75) | HPGDHTTRECQLCA12CA1 | |
| SCHEMBL6198935 | 0.84 | RECQL (0.75) | HPGDHTTRECQLCA12CA1 | |
| SCHEMBL6198934 | 0.84 | RECQL (0.75) | HPGDHTTRECQLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | NAGOYA CITY UNIVERSITY (JP) | 2013-08-08 | — | — | US | disclosed |
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | NAGOYA CITY UNIVERSITY (JP) | 2013-08-08 | — | — | US | disclosed |
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | NAGOYA CITY UNIVERSITY (JP) | 2013-08-08 | — | — | US | disclosed |
| EP-2535059-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | Public University Corporation Yokohama City University (JP) | 2012-12-19 | — | — | EP | disclosed |
| EP-2535059-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | Public University Corporation Yokohama City University (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-6143288-A | USING BORNEOL, OR RACEMIC MIXTURE THEREOF | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2000-11-07 | — | — | US | disclosed |
| EP-1042953-A2 | Use of acyclic and carbocylic ketones, alcohols, aldehydes, nitriles and esters for repelling or attracting insects | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2000-10-11 | — | — | EP | disclosed |
| EP-0660667-A1 | INSECT REPELLENT COMPOSITIONS AND METHODS FOR USING SAME. | INT FLAVORS & FRAGRANCES INC (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5401500-A | House flies attracted with benzoin group and dimethyl benzyl carbinyl acetate | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0629344-A2 | Acyclic and carbocyclic ketones, alcohols, aldehydes nitriles and esters and uses thereof for their insect repellency and attractancy properties | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5354783-A | Method for repelling Aedes aegyptae using carbocyclic ketones, and aldehyde in admixture | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994006295-A1 | INSECT REPELLENT COMPOSITIONS AND METHODS FOR USING SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1994-03-31 | — | — | WO | disclosed |
| US-5250575-A | Exposure to concentration in detergent or candle | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-5175175-A | Mixture of 1-octen-4-ol and Schiff base | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1992-12-29 | — | — | US | disclosed |
| US-5165926-A | Mosquitoes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5118711-A | Ketone, ketoesters and alcohol in repelling insects; use of aliphatic ester in attracting insects and process and apparatus for determination of insect repellency and attractancy | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-5091423-A | Using a damascone compound | INTERNATIONAL FLAVORS AND FRAGRANCES INC. (US) | 1992-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | RCOR1, MSI2, RCOR3 | HPGD 3352/4885HTT 251/4885L3MBTL1 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.