Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283401 | 0.92 | MEN1 (0.47) | MEN1KMT2APKMTHRBL3MBTL1 | |
| SCHEMBL2353115 | 0.89 | MEN1 (0.61) | MEN1KMT2APKMTHRBL3MBTL1 | |
| SCHEMBL4163475 | 0.87 | MEN1 (0.43) | MEN1KMT2APKMTHRBL3MBTL1 | |
| SCHEMBL7512444 | 0.84 | MEN1 (0.52) | MEN1KMT2APKMTHRBL3MBTL1 | |
| SCHEMBL12090949 | 0.84 | MEN1 (0.58) | MEN1KMT2APKMTHRBL3MBTL1 | |
| SCHEMBL16450969 | 0.84 | MEN1 (0.57) | MEN1KMT2APKMTHRBL3MBTL1 | |
| SCHEMBL29271676 | 0.83 | MEN1 (0.47) | MEN1KMT2APKMTHRBL3MBTL1 | |
| SCHEMBL14600833 | 0.83 | MEN1 (0.47) | MEN1KMT2APKMTHRBL3MBTL1 | |
| SCHEMBL11032395 | 0.83 | HCAR2 (0.38) | MEN1KMT2APKMTHRBL3MBTL1 | |
| SCHEMBL11174634 | 0.83 | MEN1 (0.50) | MEN1KMT2APKMTHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208014-B2 | Compositions and methods for the treatment of neurological disorders | CELLIX BIO PRIVATE LIMITED (IN) | 2019-02-19 | — | — | US | disclosed |
| US-20160122282-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | KANDULA MAHESH (IN) | 2016-05-05 | — | — | US | disclosed |
| EP-2882427-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Cellixbio Private Limited (IN) | 2015-06-17 | — | — | EP | disclosed |
| WO-2013167989-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | KANDULA MAHESH (IN) | 2013-11-14 | — | — | WO | disclosed |
| US-8450371-B2 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA, N.V. (BE) | 2013-05-28 | — | — | US | disclosed |
| US-20120322875-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | CYMABAY THERAPEUTICS, INC. | 2012-12-20 | — | — | US | disclosed |
| US-8258177-B2 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA, N.V. (BE) | 2012-09-04 | — | — | US | disclosed |
| US-20110294875-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | CYMABAY THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
| EP-0835859-B1 | Process for producing valproic acid | SIGMA TAU IND FARMACEUTI (IT) | 2000-05-03 | — | — | EP | disclosed |
| US-5856569-A | Process for producing valproic acid | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1999-01-05 | — | — | US | disclosed |
| EP-0835859-A1 | Process for producing valproic acid | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1998-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322875-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | MEN1 4870/4885KMT2A 1583/4885PKM 1190/4885 |
| US-20110294875-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | MEN1 4870/4885KMT2A 1583/4885PKM 1190/4885 |
| US-10208014-B2 | Compositions and methods for the treatment of neurological disorders | APC, PSEN1, APP | MEN1 213/4885KMT2A 3581/4885PKM 2606/4885 |
| US-20160122282-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | APC, PSEN1, BRCA1 | MEN1 191/4885KMT2A 4457/4885PKM 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.