Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12921424 | 1.00 | MEN1 (0.35) | MEN1KMT2ASMN1; SMN2MPOPTGDR2 | |
| SCHEMBL373786 | 1.00 | MEN1 (0.35) | MEN1KMT2ASMN1; SMN2MPOPTGDR2 | |
| SCHEMBL12921333 | 0.93 | NPSR1 (0.33) | MEN1KMT2ASMN1; SMN2THRB | |
| SCHEMBL186973 | 0.90 | USP2 (0.37) | MEN1KMT2ASMN1; SMN2GAATHRB | |
| SCHEMBL12921330 | 0.88 | NPSR1 (0.33) | THRB | |
| SCHEMBL12209170 | 0.87 | PTGDR2 (0.31) | PTGDR2 | |
| SCHEMBL373980 | 0.87 | PTGDR2 (0.31) | PTGDR2 | |
| SCHEMBL373406 | 0.87 | PAK4 (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8055667 | 0.87 | PAK4 (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12921328 | 0.81 | ACHE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |