⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053568 | 0.88 | AKR1B1 (0.39) | — | |
| SCHEMBL8055751 | 0.86 | AKR1A1 (0.48) | — | |
| SCHEMBL8053609 | 0.86 | AKR1B1 (0.38) | — | |
| SCHEMBL8052535 | 0.86 | AKR1A1 (0.40) | — | |
| SCHEMBL8058791 | 0.85 | AKR1B1 (0.37) | — | |
| SCHEMBL8055749 | 0.85 | AKR1B1 (0.37) | — | |
| SCHEMBL8656472 | 0.84 | AKR1A1 (0.44) | — | |
| SCHEMBL8858939 | 0.84 | AKR1A1 (0.42) | — | |
| SCHEMBL8058803 | 0.84 | AKR1B1 (0.37) | — | |
| SCHEMBL8395597 | 0.84 | SMN1; SMN2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719767-B1 | SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 2000-05-03 | — | — | EP | claimed |
| US-5688818-A | ENZYME INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-18 | — | — | US | claimed |
| EP-0719767-A1 | SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1996-07-03 | — | — | EP | claimed |
| EP-0719767-B1 | SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5688818-A | ENZYME INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| EP-0719767-A1 | SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1996-07-03 | — | — | EP | disclosed |