Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diatrizoic Acid SCHEMBL8508 | 0.98 | LMNA (0.67) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 | |
| Diatrizoic Acid SCHEMBL7615048 | 0.98 | LMNA (0.67) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 | |
| Diatrizoic Acid SCHEMBL5960726 | 0.96 | LMNA (0.65) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 | |
| Diatrizoic Acid SCHEMBL6362397 | 0.96 | LMNA (0.65) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 | |
| Diatrizoic Acid SCHEMBL30451079 | 0.96 | LMNA (0.65) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 | |
| Diatrizoic Acid SCHEMBL3974126 | 0.96 | LMNA (0.65) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 | |
| Diatrizoic Acid SCHEMBL1197801 | 0.96 | LMNA (0.65) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 | |
| Diatrizoic Acid SCHEMBL8509 | 0.96 | LMNA (0.65) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 | |
| SCHEMBL8752140 | 0.94 | LMNA (0.67) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 | |
| Diatrizoic Acid SCHEMBL28142877 | 0.92 | LMNA (0.61) | LMNASMN1; SMN2MAPK1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686046-B1 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2000-05-24 | — | — | EP | disclosed |
| US-5767299-A | Contrast agents | NYCOMED IMAGING AS (NO) | 1998-06-16 | — | — | US | disclosed |