Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL2126630 | 1.00 | — | — | |
| Glycolic Acid SCHEMBL3659535 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNASLC15A2 | |
| Glycolic Acid SCHEMBL28622711 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNASLC15A2 | |
| Glycolic Acid SCHEMBL11884631 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNASLC15A2 | |
| Glycolic Acid SCHEMBL31186420 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNASLC15A2 | |
| Glycolic Acid SCHEMBL28334467 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNLMNASLC15A2 | |
| Glycolic Acid SCHEMBL19876947 | 0.92 | — | — | |
| Acetic Acid SCHEMBL1409006 | 0.91 | — | — | |
| Propionic Acid SCHEMBL28191808 | 0.89 | FFAR3 (0.67) | FFAR3LCKFYNLMNASLC15A2 | |
| Glycolic Acid SCHEMBL3899680 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090952-A | (2R, 3S, 22R, 23R)-2,3,22,23-tetrahydroxy-24-ethyl-β-homo-7-oxa-5α-cholesta n-6-one and a process for preparing the same | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2000-07-18 | — | — | US | claimed |
| CN-111394832-B | Submicron tin dioxide fiber, preparation method thereof and application of carbon smoke catalysis | 山东大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-111394832-A | Submicron tin dioxide fiber, preparation method thereof and application of carbon smoke catalysis | 山东大学 | 2020-07-10 | — | — | CN | disclosed |
| US-6090952-A | (2R, 3S, 22R, 23R)-2,3,22,23-tetrahydroxy-24-ethyl-β-homo-7-oxa-5α-cholesta n-6-one and a process for preparing the same | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2000-07-18 | — | — | US | disclosed |