SCHEMBL8054736

SCHEMBL8054736

CCCCCCCCCCCCCCCCCCCC(=O)C(O)(CO)C(O)C(=O)CCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 7/20 0.46
▸ CES1 P23141 5/20 0.46
▸ CES2 O00748 3/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8387864 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8385578 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL10426853 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8049188 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8385671 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8049603 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL6259216 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8384672 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8384470 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL10426872 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995430-A2 Use of diacylolycerols for enhancing the barrier function of the skin Beiersdorf Aktiengesellschaft (DE) 2000-04-26 — — EP claimed
EP-0655907-B1 USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES UNIV BOSTON (US) 1999-04-28 — — EP claimed
WO-1996009810-A1 METHODS FOR ENHANCING MELANIN SYNTHESIS IN MELANOCYTES USING DIACYLGLYCEROLS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 1996-04-04 — — WO claimed
EP-0995430-A2 Use of diacylolycerols for enhancing the barrier function of the skin Beiersdorf Aktiengesellschaft (DE) 2000-04-26 — — EP disclosed
EP-0655907-B1 USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES UNIV BOSTON (US) 1999-04-28 — — EP disclosed
US-5700450-A Methods for enhancing melanin synthesis in melanocytes using diacyglycerols and uses thereof THE TRUSTEES OF BOSTON UNIVERSITY (US) 1997-12-23 — — US disclosed
US-5352440-A Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof TRUSTEES OF BOSTON UNIVERSITY (US) 1994-10-04 — — US disclosed
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