Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054890 | 1.00 | SMPD1 (0.41) | SMPD1GPR84PPARGPPARATRPV1 | |
| SCHEMBL8040562 | 0.92 | SMPD1 (0.46) | SMPD1GPR84EPHX1ESR1 | |
| SCHEMBL27527333 | 0.92 | SMPD1 (0.46) | SMPD1GPR84EPHX1ESR1 | |
| SCHEMBL9735907 | 0.90 | SMPD1 (0.44) | SMPD1GPR84EPHX1ESR1 | |
| SCHEMBL9736720 | 0.87 | SMPD1 (0.46) | SMPD1GPR84EPHX1ESR1 | |
| SCHEMBL8052978 | 0.87 | MEN1 (0.40) | SMPD1GPR84EPHX1ESR1 | |
| SCHEMBL9735678 | 0.81 | MEN1 (0.40) | SMPD1GPR84EPHX1ESR1 | |
| SCHEMBL9735531 | 0.77 | POLM (0.50) | PPARGPPARA | |
| SCHEMBL9735533 | 0.77 | POLM (0.50) | PPARGPPARA | |
| SCHEMBL9735066 | 0.76 | TLR8 (0.46) | SMPD1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-6090160-A | USE OF THE 6- OR 7-HYDROXYINDOLE COUPLER ENABLES DYEINGS WITH RESISTANCE TO LIGHT, TO WASHING, TO THE WEATHER AND TO PERSPIRATION TO BE OBTAINED, IN PARTICULAR WHEN USED WITH P-PHENYLENEDIAMINE DERIVATIVES | L'OREAL (FR) | 2000-07-18 | — | — | US | disclosed |
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | disclosed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |