Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 1/20 | 0.50 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.50 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.50 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735533 | 1.00 | POLM (0.50) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL9737235 | 0.93 | ALOX15 (0.50) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL9735599 | 0.92 | ALOX15 (0.51) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL8057870 | 0.84 | ALOX15 (0.44) | POLMPOLKPOLLPOLHALOX15 | |
| SCHEMBL8054889 | 0.83 | ALOX15 (0.45) | POLMPOLKPOLLPOLHALOX15 | |
| SCHEMBL9734923 | 0.82 | ALOX15 (0.48) | ALOX15ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL8054886 | 0.77 | SMPD1 (0.41) | PPARGPPARA | |
| SCHEMBL8054890 | 0.77 | SMPD1 (0.41) | PPARGPPARA | |
| SCHEMBL15689417 | 0.77 | MAOA (0.59) | ALDH1A1HPGDTDP1 | |
| Ammonia Solution, Strong SCHEMBL15285855 | 0.76 | ALOX15 (0.54) | POLMPOLKPOLLPOLHELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126125-A | Decreasing the melanin content in mammalian skin and hair using 5,6-dihydroxindole derivatives | YALE UNIVERSITY (US) | 1992-06-30 | — | — | US | claimed |
| US-4822375-A | LIGHTFAST, WEATHER RESISTANT, NATURAL APPEARING HAIR DYES | L'OREAL (FR) | 1989-04-18 | — | — | US | claimed |
| US-5126125-A | Decreasing the melanin content in mammalian skin and hair using 5,6-dihydroxindole derivatives | YALE UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |
| US-4956174-A | COSMETICS, TANNING, PIGMENTATION | L'OREAL (FR) | 1990-09-11 | — | — | US | disclosed |
| US-4822375-A | LIGHTFAST, WEATHER RESISTANT, NATURAL APPEARING HAIR DYES | L'OREAL (FR) | 1989-04-18 | — | — | US | disclosed |