⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24667752 | 1.00 | — | — | |
| SCHEMBL17121688 | 0.93 | — | — | |
| SCHEMBL17121689 | 0.93 | — | — | |
| SCHEMBL8555817 | 0.93 | — | — | |
| SCHEMBL12738374 | 0.91 | KMT2A (0.43) | — | |
| SCHEMBL28173258 | 0.78 | CYP1A2 (0.40) | — | |
| SCHEMBL13589975 | 0.77 | — | — | |
| SCHEMBL13654461 | 0.77 | — | — | |
| SCHEMBL15076434 | 0.76 | CASP3 (0.35) | — | |
| SCHEMBL25828687 | 0.76 | CASP3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319963-B1 | SUBSTITUTED 4-AZAINDOLES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-01-08 | — | — | EP | disclosed |
| EP-2941238-B1 | COSMETIC COMPOSITION | OREAL (FR) | 2019-10-16 | — | — | EP | disclosed |
| CN-105669664-B | Benzothiazine -4- ketone compounds containing basic nitrogen heterocyclic fragments and preparation method thereof | 浙江司太立制药股份有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | disclosed |
| EP-2961751-B1 | 1,6- DIAZABICYCLO [3,2,1]OCTAN- 7- ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | WOCKHARDT LTD (IN) | 2018-03-21 | — | — | EP | disclosed |
| WO-2017007938-A1 | SUBSTITUTED 4-AZAINDOLES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-01-12 | — | — | WO | disclosed |
| CN-105669664-A | Benzothiazine-4-ketone compounds containing basic nitrogen heterocyclic fragments and preparing methods of benzothiazine-4-ketone compounds | 浙江司太立制药股份有限公司 | 2016-06-15 | — | — | CN | disclosed |
| US-20120070385-A1 | Methods for Treating Cognitive/Attention Deficit Disorders Using Tetrahydroindolone Analogues and Derivatives | SPECTRUM PHARMACEUTICALS, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| US-8063233-B2 | Methods for treating cognitive/attention deficit disorders using tetrahydroindolone analogues and derivatives | SPECTRUM PHARMACEUTICALS INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110086866-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20090192319-A1 | METHODS FOR TREATING COGNITIVE /ATTENTION DEFICIT DISORDERS USING TETRAHYDROINDOLONE ANALOGUES AND DERIVATIVES | SPECTRUM PHARMACEUTICALS, INC. (US) | 2009-07-30 | — | — | US | disclosed |
| US-7531670-B2 | Methods for treating cognitive/attention deficit disorders using tetrahydroindolone analogues and derivatives | SPRECTRUM PHARMACEUTICALS, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| CN-100468092-C | Colored composition for color filter and color filter | TOYO INK MFG CO (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-1330984-C | Colored composition for color filter and color filter | TOPPAN PRINTING CO LTD (JP) | 2007-08-08 | — | — | CN | disclosed |
| CN-1982922-A | Colored composition for color filter and color filter | TOYO INK MFG CO (JP) | 2007-06-20 | — | — | CN | disclosed |
| CN-1307443-C | Blue colored composition for color filter and color filter | TOYO INK MFG CO LTD TOPPAN PRI (JP) | 2007-03-28 | — | — | CN | disclosed |
| CN-1673782-A | Colored composition for color filter and color filter | TOPPAN PRINTING CO LTD (JP) | 2005-09-28 | — | — | CN | disclosed |
| CN-1645170-A | Blue colored composition for color filter and color filter | TOYO INK MFG CO LTD TOPPAN PRI (JP) | 2005-07-27 | — | — | CN | disclosed |