SCHEMBL8055072

SCHEMBL8055072

O=S(=O)(O)c1ccccc1Nc1nc(Cl)nc(Cl)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.57
HPGDS O60760 1/20 0.55
NFKB1 P19838 1/20 0.47
NR4A1 P22736 1/20 0.47
MAPT P10636 3/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CHAT P28329 3/20 0.44
FUT8 Q9BYC5 3/20 0.44
USP2 O75604 1/20 0.44
APEX1 P27695 1/20 0.44
TTR P02766 1/20 0.44
FABP4 P15090 1/20 0.44
CCNA2 P20248 1/20 0.44
CDK2 P24941 1/20 0.44
MAPK14 Q16539 1/20 0.44
MEN1 O00255 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285816 0.97 HPGDS (0.57) TSHRHPGDSNFKB1NR4A1MAPT
SCHEMBL9402310 0.86 MAPT (0.51) TSHRHPGDSNR4A1MAPTKMT2A
SCHEMBL10341607 0.85 HPGDS (0.46) TSHRHPGDSNR4A1MAPTKMT2A
SCHEMBL4650519 0.84 HPGDS (0.45) TSHRHPGDSNR4A1MAPTKMT2A
SCHEMBL6849679 0.83 CHAT (0.63) HPGDSNFKB1NR4A1MAPTKMT2A
Dyrene SCHEMBL2799613 0.82 TSHR (0.60) TSHRHPGDSNFKB1NR4A1MAPT
Dyrene SCHEMBL17961257 0.82 TSHR (0.60) TSHRHPGDSNFKB1NR4A1MAPT
SCHEMBL9333401 0.82 HPGDS (0.62) HPGDSNFKB1MAPTKMT2ACHAT
Dyrene SCHEMBL8882457 0.82 TSHR (0.80) TSHRNFKB1MAPTKMT2AKDM4E
SCHEMBL10412709 0.82 TSHR (0.47) TSHRHPGDSNFKB1NR4A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8834619-B2 Ink composition, ink for inkjet recording and inkjet recording method FUJIFILM CORPORATION (JP) 2014-09-16 US disclosed
US-20140013997-A1 INK COMPOSITION, INK FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2014-01-16 US disclosed
US-8585781-B2 Azo compound, aqueous solution, ink composition, ink for inkjet recording, inkjet recording method, ink cartridge for inkjet recording, and inkjet record FUJIFILM CORPORATION (JP) 2013-11-19 US disclosed
US-20130139723-A1 NOVEL AZO COMPOUND, AQUEOUS SOLUTION, INK COMPOSITION, INK FOR INKJET RECORDING, INKJET RECORDING METHOD, INK CARTRIDGE FOR INKJET RECORDING, AND INKJET RECORD FUJIFILM CORPORATION (JP) 2013-06-06 US disclosed
EP-0557841-B1 Reactive dyes BAYER AG (DE) 2000-05-10 EP disclosed
EP-0568874-B1 Reactive dyes BAYER AG (DE) 1999-09-08 EP disclosed
US-5944854-A LEUCO DYES DYSTAR TEXTILFARBEN GMBH & CO. (DE) 1999-08-31 US disclosed
EP-0569779-B1 Reactive dyes BAYER AG (DE) 1998-07-22 EP disclosed
US-5696258-A REDUCING TO LEUCO FORM; REOXIDATION DYSTAR TEXTILFARBEN GMBH (DE) 1997-12-09 US disclosed
EP-0773264-A1 Process for the preparation of triphenodioxazine dyes amidated on both sides and triphenodioxazine dyes DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-05-14 EP disclosed
US-5160346-A PHOTOCHEMICAL AND THERMAL STABILIZATION OF POLYAMIDE FIBRE MATERIALS WITH TETRA-METHYL-PIPERIDINYL SUBSTITUTED TRIAZINE CIBA-GEIGY CORPORATION (US) 1992-11-03 US disclosed
EP-0466647-A1 Process for the photochemical and thermal stabilisation of polyamide fiber materials CIBA-GEIGY AG (CH) 1992-01-15 EP disclosed
EP-0135381-B1 REACTIVE DYES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-01-28 EP disclosed
EP-0135381-A1 Reactive dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-03-27 EP disclosed
US-4402755-A HYDROLYZED DICHLORO-S-TRIAZINE DERIVATIVE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-09-06 US disclosed
EP-0001451-B1 WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-09-23 EP disclosed
EP-0001629-B1 WATER-SOLUBLE, FIBRE-REACTIVE, GREEN AZO-PHTHALOCYANINE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-08-12 EP disclosed
EP-0001614-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their application, as well as the phthalocyanine pyrazolone intermediates and their preparation CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed
EP-0001629-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed
US-4054559-A Reactive disazo monohalogenotriazine dyestuffs NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-10-18 US disclosed